Gene description for PAPPA
Gene name pappalysin 1
Gene symbol PAPPA
Other names/aliases ASBABP2
DIPLA1
IGFBP-4ase
PAPA
PAPP-A
PAPPA1
Species Homo sapiens
 Experiment description of studies that identified PAPPA in Valvular interstitial cells

1
Experiment ID1353
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleValvular interstitial cells
Sample nameAortic valve-derived primary valvular interstial cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

2
Experiment ID1354
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleValvular interstitial cells
Sample nameAortic valve-derived primary valvular interstial cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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